Topic: Late Onset Hypogonadism, ADAM, Andropause: What Is It And What Is The Treatment?

UroToday.com - Late-onset hypogonadism (LOH), or androgen decline in the aging male, is a syndrome caused by the well-known decline in gonadal production of androgens in males that occurs with aging. It is characterized by clinical symptoms that accompany low serum androgen levels. LOH affects a wide range of organ systems and has a broad severity of clinical presentations.

Sexual dysfunction, including erectile dysfunction (ED), decreased libido, difficulty achieving orgasm, and decreased penile sensation, is usually the presenting complaint, although fatigue, depressed mood, impaired cognition, and decreased muscle mass are other common symptoms. If these symptoms are found in conjunction with low serum testosterone (T), a diagnosis of LOH may be made. Universally accepted guidelines for a level of T to define or treat LOH have not been established. In general, when the T level is found to be at or below the lower limit of normal, in conjunction with symptoms, treatment is appropriate.

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